Influenza

Japanese Encephalitis

MCV/MenB (Meningococcus)

PCV (Pneumococcus)

Rotavirus

HPV

MMR and Varicella

Herpes Zoster

RSV

Pneumococcal vaccines

Prevenar 15, PCV 20 and Pneumovax 23

Pneumococcus (Streptococcus pneumoniae) is a bacterium that causes a wide range of respiratory and generalized infections in children. It includes acute otitis media (middle ear infection), bronchitis, pneumonia (chest infection), invasive pneumococcal diseases (IPD) such as septicaemia (bacteria in the bloodstream) and meningitis (infection of brain membranes), which may be severe and life-threatening. In Hong Kong, the incidence of IPD ranges from 0.34 to 2.54 per 100,000 population from 2018 to 2022. IPD is more commonly found in young children and elderly (65 years or above). The bacteria can colonize in the nose and throat in children and the disease spreads mainly through respiratory droplets.

Young children, the elderlies, immunocompromised patients, patients with cochlear implants, patients with chronic illness (e.g., Diabetes Mellitus), and a past history of IPD are considered as high-risk groups.

The disease can be treated with antibiotics. However, there is emergence of drug-resistant strains which have made the disease more difficult to treat. Pneumococcal pneumonia is also recognized as an important co-infection of Influenza. The pneumococcal vaccines are effective against pneumococcal infections.   

Effective pneumococcal vaccines are available to prevent infections from this bacterium.

There are over 90 different serotypes of Pneumococcus. The 15-valent pneumococcal vaccine was approved by FDA in 2022 to be used in children aged 6 weeks or above. PCV 13 was replaced by PCV15 since Sept 2023. PCV20 was available in Hong Kong since April 2023 and was approved for children aged 6 weeks or above since Nov 2024.

PCV 15 and PCV 20 are conjugate vaccines that are suitable for young children (<2 years old), high-risk patients (2 years old or above), and the elderly (65 years old or above). The PCV 15 vaccine has additional coverage of the 22F and 33F serotypes compared to the Prevenar 13 vaccine. Antibody response to PCV 15 vaccine has been shown to be the same as the PCV 13 vaccine and especially to serotype 3, which is much better. PCV 15 and PCV 20 can be used interchangeably in the United States. Currently, Hong Kong has a much higher incidence of serotype 3 disease and therefore, PCV15 is recommended by the Hong Kong Government for children as the protection to serotype 3 is better. PCV20 has an additional coverage for 5 more serotypes (8, 10A, 11A, 12F and 15B).      

The 23-valent vaccine (Pneumovax 23) is an old polysaccharide vaccine. It covers additional serotypes that are not covered by Prevenar 15 and PCV 20. Vaccine authorities now recommend the 23 valent vaccines for high-risk group patients as it has a broader coverage of serotypes.  However, the 23-valent vaccine is not suitable for infants and children below 2 years of age.

The vaccines are given in 1 to 4 doses depending on the age of the recipient and individual vaccine history. Please consult our doctors for details.

Common side effects (>10 percent): local vaccination-site reactions (swelling redness, redness, and tenderness), fever, decreased appetite, tiredness, irritability. Other serious side effects (<0.1 percent): rare, seizure, severe hypersensitivity reactions

Please call our staff at 2526 6332 for information.

Please call our staff at 2526 6332 for information.